Abiaziem C.v., Afolayan, O.a., Onwuka E. D., Ozurumba G. C., Isshak F. & Okpara C. C.
Nanotechnology, as a burgeoning interdisciplinary area of research in a variety of fields, has the potential to enable breakthrough applications. There is increasing demand for chemical diversity in screening programmmes, seeking therapeutic drugs from a natural product, interest, particularly in edible plants. This study intends to quantitatively evaluate the chemical composition of sugarcane root with a pivotal aim of identifying compounds with pharmacological relevance. The GC-MS analysis of the silver nanoparticles synthesized from sugarcane root extract revealed the presence of 38 bioactive compounds while that of the magnesium oxide nanoparticle showed the presence of 27 bioactive compounds. The FT-IR spectrum was used to identify the functional groups present in sugarcane root based on the peaks values in the region of IR radiation. The sugarcane root nanoparticles FT-IR, reveal the functional groups of the components which were separated based on their peak ratio. It shows a band between 3300cm and 2900cm with a little about 2900 cm-1 . This indicates the presence of both and hydrogen-bonded OH groups and si-OH groups on the surface. The IR spectra indicated broad peaks about 1600cm-1 corresponding to-CO and –C-OH group stretching from aldehyde and ketones, there is also a transmittance in the 1000cm-1 region which indicates the presence of lactones. There is also a weak bond around 850cm-1 which might be assigned to the - OH bond. while SEM confirmed the surface morphology of the synthesized nanoparticle. Conclusively, sugarcane (Saccharum officinarum) root extract bioactive compound screening shows applauding evidence and can be considered a good source of natural therapeutic products. More comprehensive studies on the findings. KEYWORDS: nanoparticles, magnesium oxide, characterization, sugarcane, pharmaceutical 0150