Oluwafisayomi Babatola

The capacity of bioactive glasses to combine the dual functions of controlled drug release and bone regeneration has garnered them a lot of interest in recent years. But the high expense and toxicity of the conventional silica precursor, typically tetraethyl orthosilicate (TEOS), prevent the mass manufacture of bioactive glasses.. This has necessitated a paradigm shift from conventional alkoxysilanes to other silica substitutes. This research describes a novel sol-gel preparation of a silver-doped bioactive glass from biowastes as economic and eco-friendly routes to silica and calcium components of bioactive glasses. The silica was obtained from bamboo leaf while the calcium was extracted from waste chicken egg shells. The obtained bioactive glass samples were characterized for morphology and bioactivity using scanning electron microscopy (SEM). The samples' capacity to cause the creation of apatite to occur within three days of immersion in the simulated body fluid (SBF) was demonstrated by an in vitro bioactivity test, which was done using the doped sample as the control. This ability increased up until the fourteenth day at a faster rate. The results herein obtained indicates that silicate bioactive glass derived from waste bamboo leaf and eggshells can serve as candidate scaffolds in bone regeneration and a medium for release of antimicrobial agents. Keywords: Bioactive glass; bioactivity, Bone regeneration, Bamboo leaf; chicken eggshells 0150